Pyroluria

What is pyroluria?

Pyroluria is a genetic abnormal blood disorder which relates to improper haemoglobin synthesis. Haemoglobin is responsible for holding iron in red blood cells and during the production of haemoglobin there is a by-product created called kryptopyrrole.

What does pyroluria do to the body?

Kryptopyrroles have no use in the human body and people with pyroluria will produce an excessive amount of kryptopyrroles which is a chemical imbalance affecting zinc and vitamin B6 levels. Kryptopyrroles bind onto zinc and vitamin B6 and when kryptopyrroles are excreted through urine (which is their elimination process) the zinc and vitamin B6 is lost. The result of these large amounts of kryptopyrroles is a deficiency of zinc and vitamin B6 which can lead to mental and physical health issues. The more severe (higher the kryptopyrrole level) the pyroluria condition, the greater the deficiency of zinc and vitamin B6.

Below are the signs, symptoms and conditions which can be associated with pyroluria:

Abdominal pain
Acne
ADHD
Adrenaline release
Aggression
Allergies
Anger
Anxiety
Asperger's syndrome
Autism
Behavioural problems
Bipolar disorder
Cold hands and feet
Constipation
Copper imbalance
Creaking in joints
Delayed puberty
Delusions
Depression
Difficulty in remembering dreams
Dyslexia
Eczema
Emotionally unstable
Epilepsy
Fatigue
Frequent coughs and colds
Hallucinations
Heart palpitations
Hyperactivity
Hypersensitivity to noise
Hyperpigmentation of skin
Hypoglycaemia
Insomnia
Intolerance to alcohol and drugs
Intolerance to some protein foods
Lack of regular menstrual cycles

Lack of hair on head and eyebrows/ eyelashes
Learning difficulties
Loss of appetite
Low libido
Low tolerance to stress
Migraines
Mood swings
Morning nausea
Motion sickness
Nervousness
Overwhelmed in stressful situations
OCD
Pale skin, poor tanning or burn easily in sunlight
Panic attacks
Paranoia
Pessimism
Poor memory
Postnatal depression
Schizophrenia
Seizures
Sensitivity to bright light
Sensitivity to smells
Severe inner tension
Skin rashes
Social withdrawal
Substance abuse
Stress intolerance
Tingling in the arms and legs
Tremors
Toxic/heavy metal toxicity
Unusual smelling body odour
Unusual smelling breath
White spots on finger nails

Pyroluria testing

Testing for pyroluria is done through a urine sample which can be collected at home. The test measures the level of kryptopyrroles in the urine. It is a simple and easy test to complete. For pyroluria testing please click here for the available tests page.

Pyroluria treatment

Treatment for pyroluria involves dietary changes, lifestyle changes, supplement use to correct deficiencies of certain nutrients and eliminating exposure to toxins in the environment such as toxic metals. If you undergo the pyroluria test and you test positive then you will receive the treatment programme in the results email. If you have any questions about your results, then mindovermetal will answer them for you.