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Histadelia (high histamine)

​​What is histadelia?

Histadelia is a genetic metabolic/biochemical issue in which too much histamine is produced by way of too few methyl groups which are responsible for breaking down excess histamine. The result of this is elevated blood histamine levels which affect mental and physical health. Not only is histamine involved in inflammatory responses but it also acts as a neurotransmitter which is why imbalances can affect brain chemistry.
Histadelia uk
​Histadelia testing

Testing for histadelia involves a blood to check histamine levels to determine whether or not the histamine level is above the normal range. If the histamine blood level is above range then a basophil blood test will be required in order to make the histadelia diagnosis affirmative. Basophil blood count levels are high in those who have histapenia. The basophil blood test is important because high histamine blood level can sometimes be due to histamine intolerance rather than histadelia itself. Another important test for histadelia is the MTHFR gene test and other methylation analysis tests. If the methylation cycle is impaired then it affects the breakdown of histamine in the body resulting in increased histamine levels. For histadelia testing please click here for the available tests page.
Histadelia treatment
Treatment for histadelia involves dietary changes, lifestyle changes and supplement use to correct certain biochemical imbalances and to lower histamine levels. If a positive histadelia diagnosis is made then a treatment programme is sent in the results email. 
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  • Home
  • About
  • Contact
  • Content
    • A - L >
      • Adrenal Fatigue
      • Candida Overgrowth
      • Copper Toxicity
      • Histadelia
      • Histapenia
      • Histamine Intolerance (HIT)
      • Homocysteine
      • Leaky Gut Syndrome
    • M - Z >
      • MTHFR Gene Mutation
      • Methylation
      • Oxidative Stress and Free Radicals
      • Pyroluria
      • SIBO
      • Toxic Metals
  • Available tests
  • Ordering guidelines
  • FAQ
  • Advanced TRS