Fructose intolerance test UK and Europe
Order Guidelines/Laboratory Info
- Once you have paid for the test you will receive a confirmation email
- Testing laboratory - Biolab Medical Unit are based in the West End of London and they specialise in nutritional and environmental medicine offering a wide range of tests and a test referral service (for their website please click here)
- Test kit delivery - Test kits ordered before 3pm Monday to Friday will be sent out the same day. Test kits ordered after 3pm Monday to Thursday will be sent out the following day morning time. Test kits ordered after 3pm Friday and over the course of the weekend will not be sent out till Monday morning the following week
- Sample collection/sending - The test kit is sent directly to you and the sample can be collected at home. The test kit comes with instructions on how to collect the sample and comes with the relevant packaging for you to send it back to the laboratory. Once the sample has been collected you need to post the kit back to Biolab. Normal postal charges will apply (large letter rates UK). It is advised to send the sample at the start of the week so that the laboratory receives it during the same working week
- Please note: You can only order this test within Europe
- Refunds - Refunds are only possible if the test kit is unused and no samples have been sent to Biolab. If a refund is required then please email - orders@mindovermetal.co.uk, someone will then be in contact to process your refund
- Results - The test result is sent directly to you from mindovermetal Ltd and not from Biolab. The result is sent to the email that you provide when you place your order. Test results will come with an email from mindovermetal Ltd summarising your result reading. The test result is simple to understand and shows if you are above, below or within certain reference ranges. The turnaround time for results once the sample has reached the laboratory is 3 working days. Please make a note of the date you send the sample and if you do not receive your results within the time frame then please email orders@mindovermetal.co.uk and someone will be in contact
Description from Biolab
Fructose is a simple monosaccharide which is found in many plant foods. It is also used as a sweetening additive in the form of fructose corn syrup, a mixture of glucose and fructose. Its consumption is, in general, rising among the population. Setting aside the condition of hereditary fructose intolerance (which is relatively rare), it is possible for dietary intake of fructose to overload the enterocytes. This is consistent with the limited absorption capacity of the enterocyte transporter GLUT5, which is used by fructose to cross the intestinal epithelium. Non-absorbed ffructose produces gastrointestinal symptoms from its metabolism by colonic bacteria, which may be an undiagnosed cause of recurrent abdominal pain. It has also been suggested that fructose malabsorption may underlie the gastrointestinal symptoms seen in patients with irritable bowel syndrome.
The most common mutations responsible for fructose intolerance in Northern European populations are on the aldolase B gene (A149P and A174D); however these mutations only account for 80% of cases and give information as to susceptibility, rather than clinical symptoms.
Breath testing is therefore the method of choice for the diagnosis of fructose intolerance. Earlier protocols used a 50 gm dose of fructose, which often exceeded the absorptive capacity for fructose in normal individuals. 25 gm appears to be the cut-off dose to investigate fructose malabsorption, with a positive breath test at this dose suggesting abnormally low capacity to absorb fructose. This low level may be difficult to exclude from the daily diet, resulting in symptoms of fructose malabsorption.
The most common mutations responsible for fructose intolerance in Northern European populations are on the aldolase B gene (A149P and A174D); however these mutations only account for 80% of cases and give information as to susceptibility, rather than clinical symptoms.
Breath testing is therefore the method of choice for the diagnosis of fructose intolerance. Earlier protocols used a 50 gm dose of fructose, which often exceeded the absorptive capacity for fructose in normal individuals. 25 gm appears to be the cut-off dose to investigate fructose malabsorption, with a positive breath test at this dose suggesting abnormally low capacity to absorb fructose. This low level may be difficult to exclude from the daily diet, resulting in symptoms of fructose malabsorption.
